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Fosamax

by Marian Anne Eure
for About.com

Updated May 20, 2005

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

Brand Name:
Fosamax
Generic Name:
alendonate
FDA Drug Classification:
Bone-resorption inhibitor
Action:
Absorbs calcium phosphate crystal in bone; inhibits bone resorption.

Used in treatment of osteoporosis in postmenopausal women and men; prevention of osteoporosis. Also used in treatment of Pagets disease and corticosteroid-induced osteoporosis.

Adverse Effects:
Side effects that may occur include:
  • headache
  • abdominal pain, anorexia, constipation, nausea, vomiting, esophageal ulceration
  • bone pain
  • hypertension
  • UTI, fluid overload
Precautions:
Should be used with caution in children, pregnant women or those who are breastfeeding. Also use with caution in persons with esophageal disease, ulcers or gastritis.
Possible Interactions:
  • antiacids and calcium supplements may decrease absorption of this medication
  • use with NSAIDs and salycilates (aspirin) could increase gastrointestinal side effects
  • caffine and orange juice may decrease absorption of the medication
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